Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC NH-bis(PEG3-azide) | 1258939-39-7 | 98.0% | C16H33N7O6 | 250 MG
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NH-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Azide group, and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Peg-based protac linker
- Used in the synthesis of protacs
- Functions as a click chemistry reagent
- Contains an azide group
- Capable of copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
- Capable of strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
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Medchemexpress LLC Bromoacetamido-PEG3-NH-Boc | 1421933-39-2 | C15H29BrN2O6 | 5 G
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Bromoacetamido-PEG3-NH-Boc is a PEG-based PROTAC linker.
- Can be used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker.
- One ligand is for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system.
- Selectively degrade target proteins.
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Medchemexpress LLC Azido-PEG5-triethoxysilane | 3025193-22-7 | MFCD31693730 | 95.0% | C22H46N4O9Si | 25 MG
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Azido-PEG5-triethoxysilane is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, which allows it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Used in the synthesis of PROTACs.
- Functions as a click chemistry reagent.
- Contains an Azide group for copper-catalyzed azide-alkyne cycloaddition reactions.
- Can undergo strain-promoted alkyne-azide cycloaddition reactions.
- PROTACs enable selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
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Medchemexpress LLC THP-PEG5-OH | 146395-14-4 | 25 MG
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THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also described as a reference compound.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Reference compound
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Medchemexpress LLC NH2-PEG5-C6-Cl hydrochloride | 2241669-16-7 | 98.0% | 100 MG
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NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- One ligand binds to an E3 ubiquitin ligase
- The other ligand targets a specific protein
- Leverages the intracellular ubiquitin-proteasome system
- For selective degradation of target proteins
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Medchemexpress LLC Peg3-C4-Obn | 2381196-79-6 | 99.3% | 25 MG
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PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. It is utilized in the synthesis of a potent SKG3 degrader based on PROTAC.
- Liquid appearance
- Colorless to light yellow
- Purity of 99.3%
- Molecular weight of 296.40
- Molecular formula C17H28O4
- Used as a PROTAC linker
- Soluble in DMSO: ≥ 100 mg/mL
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Medchemexpress LLC THP-PEG5-OH | 50MG
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THP-PEG5-OH | 50MG
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Medchemexpress LLC I-PEG5-OH 250mg
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I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Medchemexpress LLC 1,11-bis-maleimidotetraethyleneglycol | 86099-06-1 | 98.0% | 25 MG
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BM-PEG3 is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) comprise two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. These chimeras leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is intended for research use only.
- Functions as a PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Features two distinct ligands connected by a linker
- Ligands target an E3 ubiquitin ligase and a target protein
- Employs the intracellular ubiquitin-proteasome system
- Designed for selective degradation of target proteins
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Medchemexpress LLC Ethanol, 2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]- | 60221-37-6 | 98.7% | 25 G
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THP-PEG3-OH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs feature two ligands connected by a linker, one for an E3 ubiquitin ligase and another for a target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
- High purity of 98.7%
- Molecular weight of 234.29
- Chemical formula is C11H22O5
- Appears as a liquid
- Colorless to light yellow
- Utilizes the ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 100 G
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Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- Peg-based protac linker
- Used in the synthesis of protacs
- Can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports
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Medchemexpress LLC Calcein (tetraethyl ester) | 1170856-93-5 | 99.5% | 25 MG
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Calcein tetraethyl ester is a fluorescent dye utilized in biology for evaluating cell viability and facilitating short-term cellular labeling. Its ability to permeate cellular membranes allows for transport into live cells.
- Fluorescent dye for biological applications
- Enables cell viability testing
- Suitable for short-term cell labeling
- Permeates live cell membranes
- Useful in cell staining analysis
- Applied in in vivo imaging fluorescence
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Medchemexpress LLC Aminooxy-PEG3-C2-NH-Boc | 2062663-65-2 | C13H28N2O6 | 100 MG
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Aminooxy-PEG3-C2-NH-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG- and alkyl/ether-based linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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Medchemexpress LLC Azide-PEG3-tos | 178685-33-1 | 329.37 g/mol | C13H19N3O5S | 250 MG
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Azide-PEG3-Tos is a heterobifunctional PEG linker containing an azide functional group for click chemistry. It acts as a non-cleavable, three-unit PEG linker used in the synthesis of PROTACs and antibody-drug conjugates, and participates in copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions.
- Heterobifunctional PEG linker with azide group.
- Molecular weight 329.37 g/mol.
- Chemical formula C13H19N3O5S.
- CAS number 178685-33-1.
- Available in 250 MG packaging; other sizes available.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Applications: PROTAC synthesis, ADC construction, click chemistry.
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Medchemexpress LLC Bis-PEG5-PFP ester | 1334177-78-4 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Bis-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Contains two different ligands connected by a linker.
- One ligand targets an E3 ubiquitin ligase; the other targets the protein.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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